.Writers as well as AffiliationsDana-Farber Cancer Cells Principle, Brigham as well as Womenu00e2 $ s Medical center and Harvard Medical University, Boston Ma, MA, USAToni K. Choueiriu00c2 & u00c2 William G. Kaelin JrHoward Hughes Medical Principle, Chevy Pursuit, MD, USAWilliam G. Kaelin JrCorresponding authorsCorrespondence to.Toni K. Choueiri or even William G. Kaelin Jr.